La Luz de Jesus Gallery was established in 1986 in Los Angeles, California as the brainchild of entrepreneur and art collector Billy Shire. Shire is considered largely responsible for fostering a new school of art in Los Angeles prompting JUXTAPOZ Magazine to dub him "the Peggy Guggenheim of Lowbrow."

La Luz de Jesus showcases mainly figurative, narrative paintings, and unusual sculpture. The exhibitions are considered post-pop; the art content ranges from folk to outsider to religious to sexually deviant. The gallery's main objective is to bring underground artists and counter culture to the masses.

Some of the past shows have been groundbreaking, introducing unknown artists who have become great names in the modern art world. La Luz de Jesus helped to establish artists such as Manual Ocampo and Joe Coleman, and hosted Robert Williams' art exhibits before he became a household name.

The gallery opens a new exhibit every month, with an opening reception that Details Magazine calls "the biggest and best party in Los Angeles."